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20 Oct 2017 08:37
Kite Pharma Secures FDA Approval for CAR-T Immunotherapy 
photoKite Pharma’s Yescarta (axicabtagene ciloleucel) has become the second CAR-T immunotherapy to be approved in the US, with an indication in treating adult patients with relapsed or refractory large B-cell lymphoma.

20 Oct 2017 08:36
Fallopian Tubes Found to be Site of Origin for Most Ovarian Cancers 
photoThis year, over 22,000 women will be diagnosed with ovarian cancer but a new study conducted by researchers at Perlmutter Cancer Center at NYU Langone Health suggests that most of these malignancies begin in another part of the reproductive system: the fallopian tubes.

19 Oct 2017 07:51
Study: Gender May Be Important When Matching Blood Transfusion Recipients to Donors 
photoAccording to a new study published in JAMA, gender and a history of pregnancy among female donors may have an impact on how well blood donors and recipients can be matched.

18 Oct 2017 07:33
Allergan’s Restasis Will Soon be Open to Generic Copycats After Ruling in Patent Case 
photoFour patents for Allergan’s blockbuster dry eye drug Restasis were invalidated by a federal judge on Monday, potentially leaving the drug open to generic copies.

18 Oct 2017 07:32
Is an Expanded Indication Coming for Excelixis’ Cancer Drug? 
photoSan Francisco-based biotech Excelixis has posted positive results for its cancer drug cabozantinib, which may support an expanded indication for the drug in the treatment of advanced hepatocellular carcinoma (HCC).

17 Oct 2017 07:03
Janssen’s iSTEP Mobile Clinical Trials Program Aims to Improve Medication Adherence 
photoJohnson & Johnson’s pharmaceutical division Janssen has developed a new mobile clinical trials platform to streamline clinical supply management and potentially improve patient reporting and medication adherence in these studies.

17 Oct 2017 07:02
Antihypertensive Drugs Don’t Fully Restore Microvascular Function 
photoAccording to Researchers at Lancaster University, standard treatments for high blood pressure may not be addressing damaging circulation issues in small blood vessels.

16 Oct 2017 06:56
Fluorescent Dye Helps Surgeons See Cancerous Lymph Nodes 
photoTo help identify cancerous lymph nodes, surgeons at Penn Medicine are leading a trial to see whether a fluorescent dye can be a better way to identify diseased tissue during surgery.

11 Oct 2017 06:52
New California Law Aims to Increase Transparency in Drug Pricing 
photoUnder the new law, pharmaceutical and biotech companies will be required to give 60-days notice before increasing the price of a drug more than 16 percent over two years.

10 Oct 2017 06:55
CRISPR Helps Researchers Design More Representative Preclinical Cancer Models 
photoNew research published in the journal Cell Stem Cell suggests that multiplex CRISPR-Cas9 could be used to generate mouse models of disease which could be a more accurate predictor of the human response to a drug.

05 Oct 2017 09:20
Allergan Gains Another Approval for Botox Amid Patent Controversy Over Restasis 
photoPharmaceutical company Allergan has just received another FDA approval for its blockbuster cosmetic product Botox.

04 Oct 2017 07:02
Using Next-Gen Sequencing to Detect Asymptomatic Pancreatic Cancer 
photoResearchers at the University of Pittsburgh Medical Center (UPMC) have developed a genetic test that can help identify pancreatic cancer, even when a patient experiences no obvious symptoms of disease.

03 Oct 2017 08:41
Dosing Blood Thinner Drug Based on Genetic Testing Results Could Improve Patient Safety 
photoResearch published in the Journal of the American Medical Association has found that using genetic testing results to guide dosing decisions could help mitigate the risk of warfarin-associated side effects.

02 Oct 2017 06:49
Medical Device Manufacturers More Likely to Issue Recall After Subsequent Visits from Same FDA Inspector 
photoAccording to a new study published in the journal Manufacturing & Service Operations Management, US-based medical device manufacturers could decrease their annual product recalls by as much as 20 percent if they were visited by different FDA representatives for each inspection.

28 Sep 2017 08:30
Aftermath of Brexit Could Cripple EMA 
photoA recent survey conducted by the European Medicines Agency (EMA) has found that as little as six percent of its staff would be willing to relocate once the regulatory body moves its headquarters out of London, England.

27 Sep 2017 06:47
Axovant’s Alzheimer’s Drug Fails in Phase III Clinical Trial 
photoSwiss pharmaceutical company Axovant Sciences announced yesterday that their investigational Alzheimer’s disease drug intepirdine failed to meet its co-primary endpoints in a Phase III clinical trial.

26 Sep 2017 07:13
FDA Targets Over 500 Online Pharmacies to Curb Distribution of Counterfeit Drugs 
photoThe US Food and Drug Administration (FDA) recently targeted 500 websites that sold medications, such as opioids and injectables, to patients in the US.

25 Sep 2017 07:17
25 Percent of Cancer Patients Use Cannabis to Manage Pain and Stress 
photoNearly one quarter of cancer patients treated at the Seattle Cancer Center Alliance reported that they currently use cannabis to manage the physical and psychological symptoms of treatment, according to researchers at Fred Hutchinson Cancer Research Center.

22 Sep 2017 06:52
Will Trump Demand Lower Price for Opioid Overdose Drug? 
photoDespite its status as a generic, the manufacturers of naloxone have increased the price of the medication in recent years, prompting 50 congressional members to encourage President Donald Trump to push drugmakers to lower the drug’s cost.

21 Sep 2017 07:02
Researchers Identify Role of ApoE4 Gene as Possible Drug Target in Alzheimer’s Disease 
photoA team of neurology researchers at Washington University School of Medicine in St. Louis have found that in the presence of the ApoE4 protein, another protein known as tau forms tangles in the brain which contributes to neuronal damage characteristic of Alzheimer’s disease.

20 Sep 2017 07:25
New Guidelines Address CAR-T Immunotherapy Toxicities to Prevent Patient Deaths 
photoClinicians at The University of Texas MD Anderson Cancer Center have published new guidelines in the journal, Nature Reviews Clinical Oncology, which could help in the management of these toxicities.

19 Sep 2017 07:45
Microneedle Skin Patch Could Treat Common Metabolic Disorders 
photoResearchers at Columbia University Medical Center (CUMC) and the University of North Carolina have developed a microneedle skin patch impregnated with a drug capable of converting white fat into calorie-burning brown fat.

19 Sep 2017 07:45
Allergan’s Canadian Uterine Fibroid Registry Yields Better Understanding of Condition 
photoA patent registry launched by Allergan with the aim of collecting observational data from Canadian women diagnosed with uterine fibroids is reportedly the first of its kind to compile this kind of real-world data.

18 Sep 2017 09:05
Avastin Biosimilar Becomes First FDA-Approved Copy-Cat for Cancer 
photoIn an historic event, the US Food and Drug Administration (FDA) has approved a biosimilar version of Roche’s cancer treatment Avastin (bevacizumab).

18 Sep 2017 08:49
Will an Open-Access Clinical Trials Database Improve Drug Development? 
photoNew Jersey-based business intelligence firm OZMOSI has launched a free-to-use, open-access database of clinical trial data collected from studies around the world.

15 Sep 2017 07:17
First Oral Drug for Type 1 Diabetes Could be Available in 2018 
photoA type 1 diabetes drug being codeveloped by Lexicon Pharmaceuticals and Sanofi could be the first oral treatment approved for the autoimmune disease following the release of promising Phase III clinical trial results.

15 Sep 2017 07:16
New Antibiotic Paired with Leukemia Treatment Lowers Infection Risk in Pediatric Patients 
Researchers at St. Jude Children’s Research Hospital have found an antibiotic that could help prevent patients from contracting these infections, without contributing to antibiotic resistance.

13 Sep 2017 09:34
Leica’s Fluorescence Microscope Filter Helps Surgeons See Blood Flow in the Brain 
photoThe US Food and Drug Administration (FDA) has approved Leica Microsystems’ FL560 fluorescence microscope filter to help surgeons better visualize cerebrovascular blood flow during neurosurgical procedures.

12 Sep 2017 07:10
Johnson & Johnson Stops Hepatitis C Drug Development Program 
photoIn the wake of Gilead’s string of hepatitis C therapy approvals, Johnson & Johnson’s pharmaceutical division, Janssen, has announced that it will cease development for the infectious disease.

12 Sep 2017 07:08
3,500 Job Cuts at Eli Lilly Signal Change in Focus 
photoPharmaceutical company Eli Lilly has announced it will be implementing around 3,500 layoffs globally, in an effort to “streamline operations.”

09 Aug 2017 07:15
Study Finds Common Chemotherapy Could Contribute to Cancer Metastasis 
photoChemotherapy drugs are often a key component of cancer treatment, however a new study has found a common chemotherapeutic agent, paclitaxel, could activate a pro-metastasis gene.

09 Aug 2017 07:14
Medication Adherence Startup Raises $1.6 Million in Funding 
photoUsing predictive analytics and individualized patient engagement strategies, digital health startup Groove Health hopes to improve medication adherence.

08 Aug 2017 07:26
Researchers Use CRISPR to Repair Inherited Mutation Which Causes Cardiac Condition 
photoUsing CRISPR gene editing, researchers at Oregon Health & Science University have successfully repaired a heart disease-causing mutation that can contribute to heart failure and sudden cardiac death.

08 Aug 2017 07:25
AbbVie’s 8-Week Hepatitis C Drug to Rival Gilead’s Bestselling Therapies 
photoThe US Food and Drug Administration (FDA) has just approved AbbVie’s Mavyret (glecaprevir/pibrentasvir), the first treatment for hepatitis C to show a 98 percent cure rate in as little as eight weeks.

01 Aug 2017 08:58
Clinical Trial Operations: 5 Things You’re Probably Doing Wrong 
photoElectronic data capture (EDC) and eSource are becoming increasingly common in modern clinical trials, however both of these tools are rarely integrated with any significant capability, leading to wasted time and resources.

01 Aug 2017 06:55
Depression Combined with Heart Disease Leads to Increased Death Risk 
photoAccording to researchers at Intermountain Healthcare in Salt Lake City, patients with coronary heart disease who later develop depression could be twice as likely to die, compared to non-depressed patients.

01 Aug 2017 06:53
FDA-Approved Fentanyl Drug Screening Assay to Help Identify Opioid Abuse 
photoFor the first time, the US Food and Drug Administration (FDA) has approved a urine-based immunoassay to detect fentanyl in living patients.

31 Jul 2017 07:41
Health Law Researchers Highlight Consent Problems with Biobank Sample Collection 
photoWhile biobank activity has intensified over the last several decades, a recent essay published in PLOS Biology suggests that the ethical and legal issues surrounding patient consent for sample and health information collection has yet to be standardized.

31 Jul 2017 07:41
Patient Anonymity in Clinical Trials Supported by Two De-Identification Methods 
photoA recent study – published Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research – looked at two de-identification methods for clinical trials data, known as k-anonymization and adding a “fuzzy factor.”

31 Jul 2017 07:40
760 New Genetic Drug Targets Identified by Cancer Researchers 
photoA new cancer dependency map, developed by researchers at the Broad Institute of MIT and Harvard, and the Dana-Farber Cancer Institute, has identified over 760 genes which could be potential drug targets for future anti-cancer therapies.

31 Jul 2017 07:39
Approved Alzheimer’s Drug Could Reduce Inflammation in Patients with Metabolic Syndrome 
photoA recent report published in the journal JCI Insight suggests that an existing Alzheimer’s drug could also be used to treat patients with metabolic syndrome, a condition characterized by high blood pressure, elevated glucose levels, high cholesterol and excess fat around the midline.

31 Jul 2017 07:31
The Top 4 Most Expensive Drugs in the US are Hepatitis C Treatments 
photoIn recognition of World Hepatitis Day, let’s take a look at the modern treatments capable of curing patients with hepatitis C.

24 Jul 2017 07:09
Canadian Chicken Farmers to Further Reduce Use of Antibiotics 
photoThe Chicken Farmers of Canada, a national group dedicated to supporting poultry farmers and helping them meet consumer demand for chicken, has announced their strategy for eliminating the use of certain antimicrobials in meat production.

24 Jul 2017 07:07
Neonatal MRI Medical Device Approved by the FDA 
photoMedical device maker Aspect Imaging has received US Food and Drug Administration (FDA) approval for its Embrace Neonatal MRI System.

21 Jul 2017 07:19
PhRMA Industry Group Takes Defensive Stance on Drug Pricing in New Campaign 
photoThe pharmaceutical industry trade group PhRMA has launched a campaign called “Let’s Talk About Cost” in which the lobbying group seeks to answer patients’ common questions about drug pricing.

21 Jul 2017 07:18
Gilead’s Newest Hepatitis C Drug Gets FDA Approval 
photoDominant player in the chronic hepatitis C virus (HCV) market Gilead has received US Food and Drug Administration (FDA) approval for its newest treatment, Vosevi.

19 Jul 2017 07:39
FDA Approves Puma Biotechnology’s Extended Adjuvant Therapy for Breast Cancer 
photoPuma Biotechnology’s breast cancer drug Nerlynx (neratinib) has been approved by the US Food and Drug Administration (FDA).

19 Jul 2017 07:39
CAR-T Cell Therapy Shows Promise as Leukemia Treatment in Early Stage Clinical Trial 
photoAbout 70 percent of clinical trial participants with chronic lymphocytic leukemia experienced tumor shrinkage after being treated with CAR-T immunotherapy, according to researchers at Fred Hutchinson Cancer Research Center.

17 Jul 2017 07:18
Manufacturing Control Strategies: What Pharmaceutical and Biotech Companies Need to Know 
photoOnce implemented, a manufacturing control strategy is not only beneficial for pharmaceutical companies to help them avoid product launch delays and quality concerns; patients benefit greatly from being able to rely upon the quality and increased production efficiency of drug products.

17 Jul 2017 07:18
Side Effect Risk Could Be Preventing Stroke Patients from Taking Statins 
photoResearchers in the UK have found that stroke survivors may not be taking their statin medicines as prescribed over concerns about potential side effects associated with the drugs.
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